Article
Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes.
The British journal of dermatology - 1 May 2007
Lacina L, Smetana K, Dvoránková B, Pytlík R, Kideryová L, Kucerová L, Plzáková Z, Stork J, Gabius H-J, André S
Abstract excerpt
BACKGROUND: Epithelial-mesenchymal interactions are important not only to direct the course of prenatal development of skin and its appendages but also to influence the behaviour of transformed epithelial cells. OBJECTIVES: Evaluation of the role of stromal fibroblasts on the phenotype of epithelial cells of basal cell carcinoma (BCC). METHODS: The phenotype of human BCC was compared with the in vitro model where...
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