Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes.

doi:10.1111/j.1365-2133.2006.07728.x

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Article

Stromal fibroblasts from basal cell carcinoma affect phenotype of normal keratinocytes.

The British journal of dermatology - 1 May 2007

Lacina L, Smetana K, Dvoránková B, Pytlík R, Kideryová L, Kucerová L, Plzáková Z, Stork J, Gabius H-J, André S

Abstract excerpt

BACKGROUND: Epithelial-mesenchymal interactions are important not only to direct the course of prenatal development of skin and its appendages but also to influence the behaviour of transformed epithelial cells. OBJECTIVES: Evaluation of the role of stromal fibroblasts on the phenotype of epithelial cells of basal cell carcinoma (BCC). METHODS: The phenotype of human BCC was compared with the in vitro model where...

Topics

Animals
Carcinoma, Basal Cell
Epithelial Cells
Fibroblasts
Humans
Keratinocytes
Mice
Phenotype
Skin
Skin Neoplasms
Stromal Cells

Source

Open in PubMed

Identifiers

PMID: 17263809
DOI: 10.1111/j.1365-2133.2006.07728.x

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