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Article

Nestin and SOX9 and SOX10 transcription factors are coexpressed in melanoma

21 Oct 2009

Abstract excerpt

Nestin is an intermediate filament expressed in proliferating neural progenitor cells and has been considered as a stem cell marker. Nestin is also found in melanoma and we recently demonstrated that its expression in melanoma cell lines is regulated by the transcription factors SOX9 and SOX10, but not BRN2. In this study, the expression levels of nestin, BRN2, SOX9 and SOX10 were analysed in tissues of melanoma...

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PMID: 19845757
DOI: 10.1111/j.1600-0625.2009.00991.x

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