Article
TraPS-VarI: Identifying genetic variants altering phosphotyrosine based signalling motifs.
Scientific reports - 21 May 2020
Ulaganathan Vijay Kumar
Abstract excerpt
Patient stratification and individualized therapeutic strategies rely on the established knowledge of genotype-specific molecular and cellular alterations of biological and therapeutic significance. Whilst almost all approved drugs have been developed based on the Reference Sequence protein database (RefSeq), the latest genome sequencing studies establish the substantial prevalence of non-synonymous genetic...
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