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The role of histone deacetylase 4 during chondrocyte hypertrophy and endochondral bone development

1 Feb 2020

Abstract excerpt

Chondrocyte hypertrophy represents a crucial turning point during endochondral bone development. This process is tightly regulated by various factors, constituting a regulatory network that maintains normal bone development. Histone deacetylase 4 (HDAC4) is the most well-characterized member of the HDAC class IIa family and participates in different signalling networks during development in various tissues by...

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PMID: 32435460
DOI: 10.1302/2046-3758.92.bjr-2019-0172.r1

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