Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dengue virus targets RBM10 deregulating host cell splicing and innate immune response

27 Apr 2020

Abstract excerpt

RNA-seq experiments previously performed by our laboratories showed enrichment in intronic sequences and alterations in alternative splicing in dengue-infected human cells. The transcript of the SAT1 gene, of well-known antiviral action, displayed higher inclusion of exon 4 in infected cells, leading to an mRNA isoform that is degraded by non-sense mediated decay. SAT1 is a spermidine/spermine acetyl-transferase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32432721
DOI: 10.1093/nar/gkaa340

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dengue virus targets RBM10 deregulating host cell splicing and innate immune responsePMID 32432721Read ↗

The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates SplicingSemantic proximity Read ↗

Dengue Virus Non-Structural Protein 5 as a Versatile, Multi-Functional Effector in Host–Pathogen InteractionsSemantic proximity Read ↗

The human DEAD-box protein DDX3X regulates host and viral mRNA translation during Sendai Virus infectionSemantic proximity Read ↗

Asian Zika virus isolate significantly changes the transcriptional profile and alternative RNA splicing events in a neuroblastoma cell lineSemantic proximity Read ↗

Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell LineSemantic proximity Read ↗

CircEPSTI1 regulates miR-942-5p-SERPINE1-AKT1 signaling axis to enhance dengue infection and is suppressed by TiplaxtininSemantic proximity Read ↗

ADAR mediated A-to-I RNA editing affects SARS-CoV-2 characteristics and fuels its evolutionSemantic proximity Read ↗

Direct RNA Sequencing Reveals m6A Modifications and Isoform Changes in SARS-CoV-2-Infected HEK CellsSemantic proximity Read ↗

N-acetyltransferase 10 promotes mRNA stability of immune response factors to modulate Zika virus infectionSemantic proximity Read ↗

Unraveling potential gene biomarkers for dengue infection through RNA sequencingSemantic proximity Read ↗

Viral Hijacking of Host Polyadenylation Machinery to Regulate Post-Transcriptional Gene ExpressionSemantic proximity Read ↗

RNA editing in host lncRNAs as potential modulator in SARS-CoV-2 variants-host immune response dynamicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.