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Article

RNA editing in host lncRNAs as potential modulator in SARS-CoV-2 variants-host immune response dynamics

29 Apr 2024

Abstract excerpt

Summary Both host and viral RNA editing plays a crucial role in host's response to infection, yet our understanding of host RNA editing remains limited. In this study of in-house generated RNA sequencing (RNA-seq) data of 211 hospitalized COVID-19 patients with PreVOC, Delta, and Omicron variants, we observed a significant differential editing frequency and patterns in long non-coding RNAs (lncRNAs), with Delta...

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PMID: 38770134
DOI: 10.1016/j.isci.2024.109846

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