N-acetyltransferase 10 promotes mRNA stability of immune response factors to modulate Zika virus infection

Abstract excerpt

<h4>ABSTRACT</h4> Zika virus (ZIKV) is a re-emerging mosquito-borne flavivirus that poses serious risks to human health. In previous work, we used RNA immunoprecipitation and mass spectrometry to show that more than 30 distinct RNA modifications, or chemical moieties, were present on the RNA genome of ZIKV. Among these, N4-acetylcytosine (ac 4 C) was one of the most abundant modifications. In this study, we inve...

Topics

Open a Topic to create a Post that cites this publication.

• Histone Deacetylase Inhibitors Research
• HIV Research and Treatment
• Insect symbiosis and bacterial influences
• interferon and immune responses
• Mosquito-borne diseases and control
• Peptidase Inhibition and Analysis
• RNA modifications and cancer
• Viral Infections and Vectors

Identifiers and source

Literature Corpus work

1e9a5bdd-7f28-5e63-bfc3-33eaf058671c

DOI

10.1101/2025.07.17.665358