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CircEPSTI1 regulates miR-942-5p-SERPINE1-AKT1 signaling axis to enhance dengue infection and is suppressed by Tiplaxtinin

2025-05-09

Abstract excerpt

Circular RNAs (circRNAs) have recently been identified as crucial regulators of gene expression in various diseases. Their role in dengue remains unexplored. In this study, circEPSTI1 induction was observed in peripheral blood mononuclear cells (PBMCs) and plasma of dengue patients. The induction of circEPSTI1 is interferon-dependent and enhances DENV infection by sponging the expression of miR-942-5p. The antivir...

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Literature Corpus work
77c69f67-9db7-5c3d-99be-f588442dcd55
DOI
10.1101/2025.05.05.652247
Open publication

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CircEPSTI1 regulates miR-942-5p-SERPINE1-AKT1 signaling axis to enhance dengue infection and is suppressed by TiplaxtininDOI 10.1101/2025.05.05.652247
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