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Article

Prediction of the prognosis of advanced hepatocellular carcinoma by TERT promoter mutations in circulating tumor DNA.

Journal of gastroenterology and hepatology - 1 Apr 2021

Hirai Mami, Kinugasa Hideaki, Nouso Kazuhiro, Yamamoto Shumpei, Terasawa Hiroyuki, Onishi Yuma, Oyama Atsushi, Adachi Takuya, Wada Nozomu, Sakata Masahiro, Yasunaka Tetsuya, Onishi Hideki, Shiraha Hidenori, Takaki Akinobu, Okada Hiroyuki

Abstract excerpt

BACKGROUND ANDAIM: Human telomerase reverse transcriptase (TERT) promoter mutations were the most prevalent mutations in patients with hepatocellular carcinoma (HCC). We tried to detect the mutations with plasma circulating tumor DNA (ctDNA) in patients with advanced HCC and elucidated their clinical utility. METHODS: Circulating tumor DNA in plasma was extracted from 130 patients with advanced HCC who were...

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Identifiers

PMID: 32830343
DOI: 10.1111/jgh.15227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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