Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

rs10490924 surrounding HTRA1/ARMS2 regulates the susceptibility of age-related macular degeneration.

Journal of receptor and signal transduction research - 1 Apr 2021

Tang Manhan, Li Aiyu, Wu Mingxing, Chen Xu, Xiong Xiaojing, Zhou Zixi, Liu Danning

Abstract excerpt

Multiple studies have assessed the contribution of rs10490924 on chromosome 10q26 surrounding HTRA1/ARMS2 gene to age-related macular degeneration (AMD) risk. However, the causal allele at this locus is still inconclusive. In this meta-analysis, we systematically characterized the potential association between rs10490924 polymorphism and AMD risk. Data available from 12 case-control studies, including a total of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles
Share to Genetic Association Studies
Share to Genetic Predisposition to Disease
Share to Genotype
Share to High-Temperature Requirement A Serine Peptidase 1
Share to Macular Degeneration
Share to Polymorphism, Single Nucleotide
Share to Proteins

Source

Identifiers

PMID: 32777973
DOI: 10.1080/10799893.2020.1805625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

rs10490924 surrounding HTRA1/ARMS2 regulates the susceptibility of age-related macular degeneration.PMID 32777973Read ↗

LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis.Semantic proximity Read ↗

Analysis of six genetic risk factors highly associated with AMD in the region surrounding ARMS2 and HTRA1 on chromosome 10, region q26.Semantic proximity Read ↗

Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration.Semantic proximity Read ↗

Current Views on Chr10q26 Contribution to Age-Related Macular Degeneration.Semantic proximity Read ↗

HTRA1 rs11200638 variant and AMD risk from a comprehensive analysis about 15,316 subjects.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in CFH, ARMS2 and HTRA1 genes with risk of age-related macular degeneration in Egyptian patients.Semantic proximity Read ↗

Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular DegenerationSemantic proximity Read ↗

Ongoing controversies and recent insights of the ARMS2-HTRA1 locus in age-related macular degenerationSemantic proximity Read ↗

Association of the del443ins54 at the ARMS2 locus in Indian and Australian cohorts with age-related macular degeneration.Semantic proximity Read ↗

The hypothetical molecular mechanism of the ethnic variations in the manifestation of age-related macular degeneration; focuses on the functions of the most significant susceptibility genes.Semantic proximity Read ↗

Association of LOC387715/ARMS2 (rs10490924) Gene Polymorphism with Age-Related Macular Degeneration in the Brazilian Population.Semantic proximity Read ↗

A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.