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Article

A genetic screen and transcript profiling reveal a shared regulatory program for Drosophila linker histone H1 and chromatin remodeler CHD1.

G3 (Bethesda, Md.) - 27 Jan 2015

Kavi Harsh, Lu Xingwu, Xu Na, Bartholdy Boris A, Vershilova Elena, Skoultchi Arthur I, Fyodorov Dmitry V

Abstract excerpt

Chromatin structure and activity can be modified through ATP-dependent repositioning of nucleosomes and posttranslational modifications of core histone tails within nucleosome core particles and by deposition of linker histones into the oligonucleosome fiber. The linker histone H1 is essential in metazoans. It has a profound effect on organization of chromatin into higher-order structures and on recruitment of...

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Identifiers

PMID: 25628309
DOI: 10.1534/g3.115.016709
PMCID: PMC4390582

Genes

CHD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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