Article

Genetic and Genomic Analyses of <i>Drosophila melanogaster</i> Models of Chromatin Modification Disorders

2023-04-01

Abstract excerpt

<h4>ABSTRACT</h4> Switch/Sucrose Non-Fermentable (SWI/SNF)-related intellectual disability disorders (SSRIDDs) and Cornelia de Lange syndrome are rare syndromic neurodevelopmental disorders with overlapping clinical phenotypes. SSRIDDs are associated with the BAF (Brahma-Related Gene-1 Associated Factor) complex, whereas CdLS is a disorder of chromatin modification associated with the cohesin complex. Here, we u...

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Literature Corpus work: e67b8552-f875-5297-af2a-9fee0e09e0e9
DOI: 10.1101/2023.03.30.534923

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