Article
Adapting Genotyping-by-Sequencing and Variant Calling for Heterogeneous Stock Rats.
G3 (Bethesda, Md.) - 7 Jul 2020
Gileta Alexander F, Gao Jianjun, Chitre Apurva S, Bimschleger Hannah V, St Pierre Celine L, Gopalakrishnan Shyam, Palmer Abraham A
Abstract excerpt
The heterogeneous stock (HS) is an outbred rat population derived from eight inbred rat strains. HS rats are ideally suited for genome wide association studies; however, only a few genotyping microarrays have ever been designed for rats and none of them are currently in production. To address the need for an efficient and cost effective method of genotyping HS rats, we have adapted genotype-by-sequencing (GBS) to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.