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Article

Secreted frizzled-related protein 3 was genetically and functionally associated with developmental dysplasia of the hip.

Aging - 4 Apr 2021

Xu Renjie, Zhang Fei, Lu Junlan, Wang Kexin, Pan Peng, Sun Ye, Zhang Yuxin

Abstract excerpt

BACKGROUND: Developmental dysplasia of the hip (DDH) is the most common joint disease in child orthopedics. Secreted Frizzled-Related Protein 3 (FRZB) plays an important role in joint development. however, no direct association between FRZB and DDH has been demonstrated. METHODS: Analysis of genotype distribution and allele frequency for detected single nucleotide polymorphisms (SNP) of FRZB was performed. FRZB...

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Identifiers

PMID: 33820867
DOI: 10.18632/aging.202815
PMCID: PMC8109121

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