Article
Association of insulin-like growth factor-I receptor polymorphism with colorectal cancer development.
Molecular biology reports - 1 Dec 2014
Stanilov Noyko S, Karakolev Iliya A, Deliysky Tashko S, Jovchev Jovcho P, Stanilova Spaska A
Abstract excerpt
The insulin-like growth factor (IGF) system plays a prominent role in the cancer development. The IGF-1 receptor (IGF-1R) and its associated signalling pathway is an important growth regulatory pathway that has been implicated in colorectal carcinogenesis. This study was designed to compare +3179G/A IGF1R (rs 2229765) genotype distribution in 110 colorectal cancer (CRC) patients to a group of 143 healthy controls...
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