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Evaluation of insulin like growth facror-1 genetic polymorphism with gastric cancer susceptibility and clinicopathological features.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Farahani Roya Kishani, Azimzadeh Pedram, Rostami Elham, Malekpour Habib, Aghdae Hamid Asadzadeh, Pourhoseingholi Mohamad Amin, Nazemalhosseini Mojarad Ehsan, Zali Mohammad Reza

Abstract excerpt

Gastric cancer (GC) is one of the most common malignancies in the world. It is the first cause of cancer deaths in both sexes In Iranian population. Circulating insulin-like growth factor-one (IGF-1) levels have been associated for gastric cancer. IGF-1 protein has central roles involved in the regulation of epithelial cell growth, proliferation, transformation, apoptosis and metastasis. Single nucleotide...

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PMID: 26028075
DOI: 10.7314/apjcp.2015.16.10.4215

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