Article
Effects of LDL Cholesterol and Statin Use on Verbal Learning and Memory in Older Adults at Genetic Risk for Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
Wroolie Tonita, Roat-Shumway Siena, Watson Katie, Reiman Eric, Rasgon Natalie
Abstract excerpt
BACKGROUND: The apolipoprotein epsilon 4 (APOE4) allele is a well-established genetic risk factor for Alzheimer's disease (AD). However, there are mixed findings as to how the APOE4 allele modifies the effects of both higher low-density lipoprotein cholesterol (LDL) and statin use on cognitive functioning. OBJECTIVE: This study sought to examine the effects of LDL levels and statin use on verbal learning and...
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