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Article

CXCR5/NRF2 double knockout mice develop retinal degeneration phenotype at early adult age.

Experimental eye research - 1 Jul 2020

Huang Hu, Lennikov Anton

Abstract excerpt

The objective of this study is to characterize the retinal degeneration (RD) phenotype of CXCR5/NRF2 double knockout (DKO) mice at the early adult age. CXCR5 KO mice and NRF2 KO mice were bred to create CXCR5/NRF2 DKO mice. The assessment of RD features included fundus and optical coherence tomography (OCT) imaging, periodic acid-Schiff (PAS), and immunofluorescence staining of retinal pigment epithelium...

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Source

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Identifiers

PMID: 32387618
DOI: 10.1016/j.exer.2020.108061
PMCID: PMC7456539

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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