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Article

Exercise stress test amplifies genotype-phenotype correlation in the LQT1 and LQT2 forms of the long-QT syndrome.

Circulation - 18 Feb 2003

Takenaka Kotoe, Ai Tomohiko, Shimizu Wataru, Kobori Atsushi, Ninomiya Tomonori, Otani Hideo, Kubota Tomoyuki, Takaki Hiroshi, Kamakura Shiro, Horie Minoru

Abstract excerpt

BACKGROUND: Experimental studies suggest that the interval between peak and end of T wave (Tpe) in transmural ECGs reflects transmural dispersion of repolarization (TDR), which is amplified by beta-adrenergic stimulation in the LQT1 model. In 82 patients with genetically identified long-QT syndrome (LQTS) and 33 control subjects, we examined T-wave morphology and various parameters for repolarization in 12-lead...

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PMID: 12591753
DOI: 10.1161/01.cir.0000048142.85076.a2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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