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Article

GPS2 promotes erythroid differentiation by control of the stability of EKLF protein

8 May 2020

Abstract excerpt

Erythropoiesis is a complex multistage process that involves differentiation of early erythroid progenitors to enucleated mature red blood cells, in which lineage-specific transcription factors play essential roles. Erythroid Krüppel-like factor (EKLF/KLF1) is a pleiotropic erythroid transcription factor that is required for the proper maturation of the erythroid cells, whose expression and activation are tightly...

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PMID: 32384137
DOI: 10.1182/blood.2019003867

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