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Article

Uncoding the genetic heterogeneity of myelodysplastic syndrome.

Hematology. American Society of Hematology. Education Program - 8 Dec 2017

Lindsley R Coleman

Abstract excerpt

Myelodysplastic syndrome (MDS) is a clinically heterogeneous disease characterized by functional impairment of hematopoiesis and abnormal bone marrow morphology. The type and severity of hematopoietic dysfunction in MDS are highly variable, and the kinetics of disease progression are difficult to predict. Genomic studies have shown that MDS is typically driven by a multistep somatic genetic process affecting a...

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Identifiers

PMID: 29222292
DOI: 10.1182/asheducation-2017.1.447
PMCID: PMC6142603

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