Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted RNA sequencing for upfront analysis of actionable driver alterations in non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 2022

Claerhout Sofie, Lehnert Stefan, Vander Borght Sara, Spans Lien, Dooms Christophe, Wauters Els, Vansteenkiste Johan, Weynand Birgit, Deraedt Karen, Bourgain Claire, Vanden Bempt Isabelle

Abstract excerpt

OBJECTIVES: Targeted RNA-based Next-Generation Sequencing (tRNA-seq) is increasingly being used in molecular diagnostics for gene fusion detection in non-small cell lung cancer (NSCLC). However, few data support its clinical application for the detection of single nucleotide variants (SNVs) and small insertions/deletions. In this study, we evaluated the performance of tRNA-seq using Archer FusionPlex for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Lung Neoplasms

Share to Mutation

Share to Sequence Analysis, RNA

Source

Identifiers

PMID: 35378489
DOI: 10.1016/j.lungcan.2022.02.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted RNA sequencing for upfront analysis of actionable driver alterations in non-small cell lung cancer.PMID 35378489Read ↗

Detection of multiple types of cancer driver mutations using targeted RNA sequencing in non-small cell lung cancer.Semantic proximity Read ↗

Detection of Multiple Types of Cancer Driver Mutations Using Targeted RNA Sequencing in NSCLCSemantic proximity Read ↗

Clinical Validation of a Targeted RNA-Sequencing Assay for Driver Gene Alteration Detection in Non-Small Cell Lung Cancer.Semantic proximity Read ↗

Successive next-generation sequencing strategy for optimal fusion gene detection in non-small-cell lung cancer in clinical practice.Semantic proximity Read ↗

Analysis of rare fusions in NSCLC: Genomic architecture and clinical implications.Semantic proximity Read ↗

Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer.Semantic proximity Read ↗

Simultaneous detection of single-nucleotide variant, deletion/insertion, and fusion in lung and thyroid carcinoma using cytology specimen and an RNA-based next-generation sequencing assay.Semantic proximity Read ↗

Actionable Structural Variant Detection via RNA-NGS and DNA-NGS in Patients With Advanced Non–Small Cell Lung CancerSemantic proximity Read ↗

Fusion‐positive non‐small cell lung carcinoma: Biological principles, clinical practice, and diagnostic implicationsSemantic proximity Read ↗

Tumor molecular profiling of NSCLC patients using next generation sequencing.Semantic proximity Read ↗

Molecular profiling and feasibility using a comprehensive hybrid capture panel on a consecutive series of non-small-cell lung cancer patients from a single centreSemantic proximity Read ↗

Detection of gene fusions using targeted next-generation sequencing: a comparative evaluationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.