Article
Detection of multiple types of cancer driver mutations using targeted RNA sequencing in non-small cell lung cancer.
Cancer - 1 Aug 2023
Ju Sheng, Cui Zihan, Hong Yuanyuan, Wang Xiaoqing, Mu Weina, Xie Zhuolin, Zeng Xuexia, Su Lin, Lin Xiaojing, Zhang Zhuo, Zhang Qi, Song Xiaofeng, You Songxia, Chen Ruixin, Chen Weizhi, Xu Chun, Zhao Jun
Abstract excerpt
BACKGROUND: DNA-based next-generation sequencing has been widely used in the selection of target therapies for patients with nonsmall cell lung cancer (NSCLC). RNA-based next-generation sequencing has been proven to be valuable in detecting fusion and exon-skipping mutations and is recommended by National Comprehensive Cancer Network guidelines for these mutation types. METHODS: The authors developed an RNA-based...
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