Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia.

The Journal of cell biology - 1 Jun 2020

Liu Peiwei, Lou Xiaochu, Wingfield Jenna L, Lin Jianfeng, Nicastro Daniela, Lechtreck Karl

Abstract excerpt

Mutations in the channel protein PKD2 cause autosomal dominant polycystic kidney disease, but the function of PKD2 in cilia remains unclear. Here, we show that PKD2 targets and anchors mastigonemes, filamentous polymers of the glycoprotein MST1, to the extracellular surface of Chlamydomonas cilia. PKD2-mastigoneme complexes physically connect to the axonemal doublets 4 and 8, positioning them perpendicular to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axoneme
Share to Cell Movement
Share to Chlamydomonas

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycoproteins

Share to Mutation

Share to Polymers

Share to Transient Receptor Potential Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 32348466
DOI: 10.1083/jcb.202001122
PMCID: PMC7265326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia.PMID 32348466Read ↗

Ciliary mechanosensation - roles of polycystins and mastigonemes.Semantic proximity Read ↗

De novo identification of mammalian ciliary motility proteins using cryo-EM.Semantic proximity Read ↗

Tracking N- and C-termini of <i>C. elegans</i> polycystin-1 reveals their distinct targeting requirements and functions in cilia and extracellular vesiclesSemantic proximity Read ↗

Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2aSemantic proximity Read ↗

Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50.Semantic proximity Read ↗

Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus.Semantic proximity Read ↗

Structural organization of the C1b projection within the ciliary central apparatusSemantic proximity Read ↗

The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella.Semantic proximity Read ↗

Dissecting the axoneme interactome: the mammalian orthologue of Chlamydomonas PF6 interacts with sperm-associated antigen 6, the mammalian orthologue of Chlamydomonas PF16.Semantic proximity Read ↗

Primary ciliary dyskinesia relative protein ZMYND10 is involved in regulating ciliary function and intraflagellar transport in Paramecium tetraurelia.Semantic proximity Read ↗

Spatial Control of Primary Ciliogenesis by Subdistal Appendages Alters Sensation-Associated Properties of Cilia.Semantic proximity Read ↗

Composition and function of ciliary inner-dynein-arm subunits studied in Chlamydomonas reinhardtii.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.