Article
Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50.
Molecular biology of the cell - 1 Apr 2011
Yang Yong, Cochran Deborah A, Gargano Mary D, King Iryna, Samhat Nayef K, Burger Benjain P, Sabourin Katherine R, Hou Yuqing, Awata Junya, Parry David A D, Marshall Wallace F, Witman George B, Lu Xiangyi
Abstract excerpt
Eukaryotic cilia and flagella are vital sensory and motile organelles. The calcium channel PKD2 mediates sensory perception on cilia and flagella, and defects in this can contribute to ciliopathic diseases. Signaling from Pkd2-dependent Ca²+ rise in the cilium to downstream effectors may require intermediary proteins that are largely unknown. To identify these proteins, we carried out genetic screens for...
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