Article
Spatial Control of Primary Ciliogenesis by Subdistal Appendages Alters Sensation-Associated Properties of Cilia.
Developmental cell - 21 Nov 2016
Mazo Gregory, Soplop Nadine, Wang Won-Jing, Uryu Kunihiro, Tsou Meng Fu Bryan
Abstract excerpt
Vertebrate cells can initiate ciliogenesis from centrioles at the cell center, near the Golgi, forming primary cilia confined or submerged in a deep narrow pit created by membrane invagination. How or why cells maintain submerged cilia is unclear. Here, by characterizing centriole subdistal appendages (sDAP) in cells exclusively growing submerged cilia, we found that a group of sDAP components localize to the...
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