Do different IgG repertoires play a role in B‐ and T‐cell functional modulation during ontogeny? The “hooks without bait” theory

Abstract excerpt

The mechanisms by which immunoglobulin (Ig)G can modulate immunity have been investigated over the past few decades. In the past three years, some studies have demonstrated that IgG can play a pivotal role in mediating complex interactions that result in functional lymphocyte modulation during maturation in self or offspring primary lymphoid organs. This effect appears to be dependent on the IgG repertoire in the...

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