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Article

Altered ARID1A expression in colorectal cancer

25 Apr 2020

Abstract excerpt

BACKGROUND: ARID1A has been described as a tumor suppressor gene, participating in chromatin re-modeling, epithelial-mesenchymal-transition and many other cellular and molecular processes. It has been cited as a contribute in tumorigenesis. The role of ARID1A in CRC is not yet defined. AIM: To investigate the role of ARID1A methylation and CNV in its expression in CRC cell lines and to examine the relationship...

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PMID: 32334542
DOI: 10.1186/s12885-020-6706-x

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