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Article

Loss of ARID1A expression in colorectal carcinoma is strongly associated with mismatch repair deficiency.

Human pathology - 1 Aug 2014

Chou Angela, Toon Christopher W, Clarkson Adele, Sioson Loretta, Houang Michelle, Watson Nicole, DeSilva Keshani, Gill Anthony J

Abstract excerpt

ARID1A is a tumor suppressor gene involved in chromatin remodelling. ARID1A mutations and loss of protein expression occur commonly in endometrioid and gynecological clear cell carcinoma where they are associated with mismatch repair (MMR) deficiency. We assessed ARID1A expression in a large coho...

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Identifiers

PMID: 24925223
DOI: 10.1016/j.humpath.2014.04.009

Genes

BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24925223-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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