Article
Admixture mapping of ankle-arm index: identification of a candidate locus associated with peripheral arterial disease.
Journal of medical genetics - 1 Jan 2010
Scherer M L, Nalls M A, Pawlikowska L, Ziv E, Mitchell G, Huntsman S, Hu D, Sutton-Tyrrell K, Lakatta E G, Hsueh W-C, Newman A B, Tandon A, Kim L, Kwok P-Y, Sung A, Li R, Psaty B, Reiner A P, Harris T
Abstract excerpt
BACKGROUND: Peripheral arterial disease (PAD) is associated with significant morbidity and mortality, and has a higher prevalence in African Americans than Caucasians. Ankle-arm index (AAI) is the ratio of systolic blood pressure in the leg to that in the arm, and, when low, is a marker of PAD. METHODS: The authors used an admixture mapping approach to search for genetic loci associated with low AAI. Using data...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.