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Article

Pretreatment HIV drug resistance predicts accumulation of new mutations in ART-naïve Ugandan children.

Acta paediatrica (Oslo, Norway : 1992) - 1 Dec 2020

Soeria-Atmadja Sandra, Amuge Pauline, Nanzigu Sarah, Bbuye Dickson, Rubin Johanna, Eriksen Jaran, Kekitiinwa Adeodata, Obua Celestino, Gustafsson Lars L, Navér Lars

Abstract excerpt

AIM: To assess the prevalence of pretreatment drug resistance (PDR) and its association with virologic outcomes after 24 weeks of antiretroviral therapy (ART), within an urban cohort of Ugandan children. METHODS: Prospective observational study. Baseline and 24-week assessments of viral load (VL) and genotypic drug resistance to nucleoside reverse transcriptase inhibitors (NRTI) and non-nucleoside reverse...

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Anti-HIV Agents
Child
Drug Resistance, Viral
Genotype
HIV-1

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PMID: 32304595
DOI: 10.1111/apa.15320

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