Article
Antiretroviral drug resistance profiles and response to second-line therapy among HIV type 1-infected Ugandan children.
AIDS research and human retroviruses - 1 Mar 2013
Musiime Victor, Kaudha Elizabeth, Kayiwa Joshua, Mirembe Grace, Odera Matthew, Kizito Hilda, Nankya Immaculate, Ssali Francis, Kityo Cissy, Colebunders Robert, Mugyenyi Peter
Abstract excerpt
We sought to determine the pattern of resistance-associated mutations (RAMs) among HIV-1-infected children failing first-line antiretroviral therapy (ART) and ascertain their response to second-line regimens in 48 weeks of follow-up. The design involved a cohort study within an HIV care program. We studied records of 142 children on ART with virological failure to first-line ART and switched to second-line ART...
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