Article
Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy.
AIDS research and human retroviruses - 1 Jun 2013
Sigaloff Kim C E, Kayiwa Joshua, Musiime Victor, Calis Job C J, Kaudha Elizabeth, Mukuye Andrew, Matama Christine, Nankya Immaculate, Nakatudde Lillian, Dekker John T, Hamers Raph L, Mugyenyi Peter, Rinke De Wit Tobias F, Kityo Cissy
Abstract excerpt
HIV-infected children are at high risk of acquiring drug-resistant viruses, which is of particular concern in settings where antiretroviral drug options are limited. We aimed to assess resistance patterns and predict viral drug susceptibility among children with first-line antiretroviral therapy (ART) failure in Uganda. A cross-sectional analysis of children switching ART regimens due to first-line failure was...
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