Article
Prevalence of Pre-antiretroviral-Treatment Drug Resistance by Gender, Age, and Other Factors in HIV-Infected Individuals Initiating Therapy in Kenya, 2013-2014.
The Journal of infectious diseases - 19 Dec 2017
Silverman Rachel A, Beck Ingrid A, Kiptinness Catherine, Levine Molly, Milne Ross, McGrath Christine J, Bii Steve, Richardson Barbra A, John-Stewart Grace, Chohan Bhavna, Sakr Samah R, Kiarie James N, Frenkel Lisa M, Chung Michael H
Abstract excerpt
Background: Pre-antiretroviral-treatment drug resistance (PDR) is a predictor of human immunodeficiency virus (HIV) treatment failure. We determined PDR prevalence and correlates in a Kenyan cohort. Methods: We conducted a cross-sectional analysis of antiretroviral (ARV) treatment-eligible HIV-infected participants. PDR was defined as ≥2% mutant frequency in a participant's HIV quasispecies at pol codons K103N,...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Cross-Sectional Studies
- Drug Resistance, Viral
- Female
- Genotype
- Genotyping Techniques
- HIV