Article
High Prevalence of HIV Drug Resistance Among Newly Diagnosed Infants Aged <18 Months: Results From a Nationwide Surveillance in Nigeria.
Journal of acquired immune deficiency syndromes (1999) - 1 Jan 2018
Inzaule Seth C, Osi Samuels J, Akinbiyi Gbenga, Emeka Asadu, Khamofu Hadiza, Mpazanje Rex, Ilesanmi Oluwafunke, Ndembi Nicaise, Odafe Solomon, Sigaloff Kim C E, Rinke de Wit Tobias F, Akanmu Sulaimon
Abstract excerpt
BACKGROUND: WHO recommends protease-inhibitor-based first-line regimen in infants because of risk of drug resistance from failed prophylaxis used in prevention of mother-to-child transmission (PMTCT). However, cost and logistics impede implementation in sub-Saharan Africa, and >75% of children still receive nonnucleoside reverse transcriptase inhibitor-based regimen (NNRTI) used in PMTCT. METHODS: We assessed the...
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