Article
13C-caffeine breath test identifies single nucleotide polymorphisms associated with caffeine metabolism.
Drug metabolism and pharmacokinetics - 1 Jun 2020
Ishii Michiko, Ishii Yukimoto, Nakayama Tomohiro, Takahashi Yasuo, Asai Satoshi
Abstract excerpt
We performed a caffeine (N-3-methyl-13C) breath test (CafeBT) to determine whether it can be employed to identify caffeine metabolism-associated single nucleotide polymorphisms. The study included 130 healthy adults (mean age: 21.9 years). Saliva was collected using an Oragene®•DNA saliva collection kit. Breath samples were collected from the subjects. The subjects orally ingested 100 mg 13C-caffeine dissolved in...
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