Article
Evaluating the performance of a genetic test using information from previous studies in place of a gold standard.
Medical care - 1 Aug 1998
Fijal B A, Witte J S
Abstract excerpt
OBJECTIVES: To evaluate the performance of a diagnostic test, a researcher usually must classify study subjects with respect to (1) whether the test result was positive or negative and (2) whether the test result should have been positive or negative. To classify the subjects in the second manner...
Topics
- Breast Neoplasms
- Evidence-Based Medicine
- Female
- Genes, BRCA1
- Genetic Diseases, Inborn
- Genetic Markers
- Genetic Testing
- Genotype
- Humans
- Mutation
- Prevalence
- Recombination, Genetic
- Reproducibility of Results