Article
Unified method for Bayesian calculation of genetic risk.
Journal of human genetics - 1 Jan 2006
Kuno Shin-Ichi, Furihata Shiori, Itou Toshikazu, Saito Kayoko, Kamatani Naoyuki
Abstract excerpt
Bayesian inference has been used for genetic risk calculation. In this traditional method, inheritance events are divided into a number of cases under the inheritance model, and some elements of the inheritance model are usually disregarded. We developed a genetic risk calculation program, GRISK, which contains an improved Bayesian risk calculation algorithm to express the outcome of inheritance events with...
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