Article
[Association between single nucleotide polymorphism in promoter region of SIRT1 gene and senile degenerative heart valvular disease].
Zhonghua yi xue za zhi - 7 Apr 2020
Song Z P, Li J R, Gao R, Cui Y H, Pang S C, Yan B
Abstract excerpt
Objective: To investigate the correlation between single nucleotide polymorphisms (SNPs) of SIRT1 gene promoter sequence and senile degenerative heart valvular disease (SDHVD). Methods: A total of 236 SDHVD patients and 285 healthy controls who visited the Affiliated Hospital of Jining Medical University between February 2012 and October 2016 were enrolled. SNPs of SIRT1 gene promoter were detected by Sanger...
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