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Article

The effect of the SIRT1 2827 A>G polymorphism, resveratrol, exercise, age and occupation in Turkish population with cardiovascular disease.

Anatolian journal of cardiology - 1 Feb 2015

İzmirli Müzeyyen, Göktekin Ömer, Bacaksız Ahmet, Uysal Ömer, Kılıç Ülkan

Abstract excerpt

OBJECTIVE: Cardiovascular disease (CVD) is the leading cause of death in Europe. One of the candidate molecule affecting epigenetic mechanisms of CVD is the SIRT1, a subclass of sirtuins, is located on the long arm of chromosome 10 (10q21.3). Particularly, the relation between 2827 A>G polymorphism of the SIRT1 positioned on exon 2, leading to conversion of histidine to arginine, and the formation of CVD is not...

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Identifiers

PMID: 25252293
DOI: 10.5152/akd.2014.5214
PMCID: PMC5336992

Genes

SIRT1

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