Article
The effect of SIRT1 gene polymorphisms on ambulatory blood pressure of hypertensive patients in the Kazakh population.
Genetic testing and molecular biomarkers - 1 Oct 2015
Zhong Xiao-Lan, Miao Hai-Jun, Fang Zhi-Min, Kuken Bannu, Song Hong-Yan, Zhong Hua, Lu Yun, Liu Shun-Min
Abstract excerpt
OBJECTIVE: To investigate the effect of silent information regulator 1 (SIRT1) gene polymorphisms on ambulatory blood pressure in hypertensive patients. METHODS: Three hundred forty hypertensive patients were recruited from January 2013 to January 2015. SIRT1 Tag single-nucleotide polymorphisms (SNPs; rs2273773, rs4746720, and rs7896005) were genotyped using a PCR-direct sequencing method, and the association...
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