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Article

Gene polymorphisms of SIRT1 in patients with rheumatoid arthritis.

International journal of rheumatic diseases - 1 Feb 2022

Zhou Jie, He Yan-Wei, Fu Lu, Lan You-Yu, Liu Xiao-Yan, Wu Qian, Xu Wang-Dong, Huang An-Fang

Abstract excerpt

AIM: Previous studies have shown that silent information regulator 1 (SIRT1) expression is elevated in rheumatoid arthritis (RA) patients. However, whether gene polymorphisms in SIRT1 gene associated with RA in a Chinese Han population remains to be discussed. METHOD: In this case-control study, 529 RA patients and 700 healthy controls were selected, and association of 11 SIRT1 gene polymorphisms (rs12415800,...

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Arthritis, Rheumatoid
Case-Control Studies
China

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 34866331
DOI: 10.1111/1756-185X.14257

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