Article
Neuroblastoma-Telomere maintenance, deregulated signaling transduction and beyond.
International journal of cancer - 15 Mar 2022
Stainczyk Sabine A, Westermann Frank
Abstract excerpt
The childhood malignancy neuroblastoma belongs to the group of embryonal tumors and originates from progenitor cells of the sympathoadrenal lineage. Treatment options for children with high-risk and relapsed disease are still very limited. In recent years, an ever-growing molecular diversity was identified using (epi)-genetic profiling of neuroblastoma tumors, indicating that molecularly targeted therapies could...
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