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Article

Somatic ASXL1 p.R693X mutation identified by next generation sequencing in isolated myeloid sarcoma involving the mediastinum.

Current medical research and opinion - 1 Jun 2020

Fang Liwei, Cui Yajuan, Mi Yingchang, Ru Kun, Sun Qi, Qin Tiejun, Xu Zefeng, Wang Jianxiang, Xiao Zhijian

Abstract excerpt

Introduction: Isolated myeloid sarcoma (MS) is characterized by extramedullary immature myeloid cell infiltration without bone marrow involvement. The diagnosis of isolated MS is sometimes difficult in cases without expression of typical immunohistochemical markers, such as CD64, MPO or lysozyme.Clinical presentation: We report a case of isolated MS involving the mediastinum, with negative staining of MPO and...

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PMID: 32286099
DOI: 10.1080/03007995.2020.1744121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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