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Article

RNA sequencing of myeloid sarcoma, shed light on myeloid sarcoma stratification.

Cancer medicine - 1 Apr 2023

Yang Yunfan, Shu Yang, Tang Yuan, Zhao Sha, Jia Yongqian, Ji Jie, Ma Hongbing, Lin Ting, Zheng Ke, Xu Heng, Wu Yu

Abstract excerpt

BACKGROUND: Myeloid sarcoma (MS) is a rare, extramedullary tumor consisting of myeloid blasts. Little is known about the genetic background of MS and the prognostic value of genetic abnormalities in MS. In particular, the broad variety of gene fusions that occur in MS is marginally covered by traditional testing methods due to lack of fresh tumor specimens. METHODS: Here, we analyzed the clinical and genetic...

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PMID: 36916780
DOI: 10.1002/cam4.5654
PMCID: PMC10166975

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