Article
Molecular subtype, biological sex and age shape melanoma tumour evolution.
The British journal of dermatology - 1 Feb 2021
Lotz M, Budden T, Furney S J, Virós A
Abstract excerpt
BACKGROUND: Many cancer types display sex and age disparity in incidence and outcome. The mutational load of tumours, including melanoma, varies according to sex and age. However, there are no tools to explore systematically whether clinical variables such as age and sex determine the genomic landscape of cancer. OBJECTIVES: To establish a mathematical approach using melanoma mutational data to analyse how sex...
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