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Article

CScape-somatic: distinguishing driver and passenger point mutations in the cancer genome.

Bioinformatics (Oxford, England) - 1 Jun 2020

Rogers Mark F, Gaunt Tom R, Campbell Colin

Abstract excerpt

MOTIVATION: Next-generation sequencing technologies have accelerated the discovery of single nucleotide variants in the human genome, stimulating the development of predictors for classifying which of these variants are likely functional in disease, and which neutral. Recently, we proposed CScape, a method for discriminating between cancer driver mutations and presumed benign variants. For the neutral class, this...

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Identifiers

PMID: 32282885
DOI: 10.1093/bioinformatics/btaa242
PMCID: PMC7320610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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