Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR gene) with ischemic stroke: a meta-analysis.

doi:10.1179/1743132815Y.0000000008

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Article

Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR gene) with ischemic stroke: a meta-analysis.

Neurological research - 1 Jul 2015

Kumar Amit, Kumar Pradeep, Prasad Manya, Sagar Ram, Yadav Arun Kumar, Pandit Awadh Kishor, Jali Vidishaa Prasad, Pathak Abhishek

Abstract excerpt

OBJECTIVE: Studies on association between methylenetetrahydrofolate reductase gene (MTHFR) C677T gene polymorphism and ischemic stroke have shown conflicting results. We have conducted a meta-analysis to determine the precise association of the C677T polymorphism of MTHFR gene with risk of ischem...

Topics

Asian People
Brain Ischemia
Genetic Predisposition to Disease
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Models, Genetic
Polymorphism, Genetic
Publication Bias
Stroke
White People

Source

Open in PubMed

Identifiers

PMID: 25591425
DOI: 10.1179/1743132815Y.0000000008

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25591425-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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