Article
Methylenetetrahydrofolate reductase polymorphisms and homocysteine-lowering effect of vitamin therapy in Singaporean stroke patients.
Stroke - 1 Feb 2006
Ho Grace Y-H, Eikelboom John W, Hankey Graeme J, Wong Chen-Ru, Tan Siew-Li, Chan Jesscia B-C, Chen Christopher P L-H
Abstract excerpt
BACKGROUND AND PURPOSE: Increased plasma total homocysteine (tHcy) levels are a risk factor for stroke and can be reduced with vitamin therapy. However, data on the tHcy-lowering effects of vitamins are limited largely to white populations. Thus, we aimed to determine in Singaporean patients with recent stroke: (1) the efficacy of vitamin therapy (folic acid, vitamin B12, and B6) on lowering tHcy, and (2) whether...
Topics
- Aged
- Coronary Artery Disease
- Dietary Supplements
- Female
- Folic Acid
- Follow-Up Studies
- Genetic Predisposition to Disease
- Genotype
- Homocysteine
- Humans
- Hyperhomocysteinemia
- Ischemic Attack, Transient
- Male