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Article

Effects of neural estrogen receptor beta deletion on social and mood-related behaviors and underlying mechanisms in male mice.

Scientific reports - 10 Apr 2020

Dombret Carlos, Naulé Lydie, Trouillet Anne-Charlotte, Parmentier Caroline, Hardin-Pouzet Hélène, Mhaouty-Kodja Sakina

Abstract excerpt

Estradiol derived from neural aromatization of testosterone plays a key role in the organization and activation of neural structures underlying male behaviors. This study evaluated the contribution of the estrogen receptor (ER) β in estradiol-induced modulation of social and mood-related behaviors by using mice lacking the ERβ gene in the nervous system. Mutant males exhibited reduced social interaction with...

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Identifiers

PMID: 32277160
DOI: 10.1038/s41598-020-63427-4
PMCID: PMC7148327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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